Two fire crews from March and one crew from Chatteris were called to a road traffic collision on the A141 in Wimblington on Friday night.
Two vehicles were involved and firefighters used specialist cutting equipment to release two casualties, who were taken to hospital by ambulance.
Crews returned to their stations by 8.50pm.
PC Andy Coop from the Roads Policing Unit would like to hear from you if you witnessed the collision or saw the vehicles prior to the collision.
Anyone with any information should call PC Coop on 101.
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